I have been lucky enough to pick up once fired brass at the gun shows....sometimes.I would say we will see lots of different calibers of new brass from the big boys will get harder to buy new. They can't keep up with manufacturing ammunition why would they sell brass to reloaders? Lots of powders are going up big time again soon.
22-250 brass will be available in the once fired market and by the smaller manufactures for the next 50 years at least.