Will you take the Covid Vaccine?

[churchmouse]

Tonight I heard of another who got sick after #2 shot. Not put an actual number on this but far to many.

You all just go ahead and do you. Me and mine no ****ing way OK

 

[churchmouse]

I received my second dose (Moderna) 2 days ago. I had the expected response starting late Wed night and through Thursday: headache, fatigue, mild chills. I had taken the day off of work so it was not a big problem. I'm 100% normal today.

Unfortunately, still no 5G reception

My 87 yr old parents received their first dose in Illinois today. Illinois vaccine rollout is a clusterf*** compared to Indiana. I had to make multiple phone calls to finally get them scheduled.

Its Illinois after all you know...

 

[dusty88]

The more time goes by, the more I think Indiana is doing this right by vaccinating the most vulnerable rather than trying to choose "frontline essential". There is legitimate concern that a more contagious variant is developing here, as it did in the UK. If so, it's going to cause another surge before we can get a vaccine in everyone that wants it. By targeting everyone over 60, Indiana is targeting 94% of the deaths and 60% of the hospitalizations. It sounds like after that they might focus on comorbidities rather than age, but are using data to make that decision.

I don't want to see anyone get sick, but keeping the hospital cases down is better for all of us. If an unlucky 19 yr old ends up with severe Covid, he's better off with a nursing staff that is not overwhelmed. Also, if you need an elective surgery, the hospital needs spare ICU beds in order to go forward with those.

I hope the concern of another surge is wrong. But if it does happen, I think Indiana will be better-prepared than our surrounding states. I know "teachers" have been a hotbutton issue. It gets brought up by the press about 3x at each Covid conference. I want to see teachers protected (or offered remote options if they want it). But there are a lot of people who have to work around others, not just teachers. Focusing on those most likely to get a severe illness makes sense to me.

 

[dusty88]

Why do you say a bunch more people will have to get Covid and recover from it for herd immunity? Per the article herd immunity will require 70-85% to be immune, 75% say they will take the vaccine that more than meets the lower threshold, and only 10% shy of the upper. What percent of people have already had and recovered from it? Best I can find is about 7.8% of the population in the US have had it, unknown about the percent recovered/died.

I think the estimated number of previous cases in the US includes about 30% of the population (taking into account asymptomatic, untested).

Herd immunity for a respiratory disease is typically thought to take about 70%. However, the data on increased contagion of new variants looks real. And it makes sense, because such a mutation is going to have an evolutionary advantage for the virus. If the virus is more contagious, it's going to take something closer to 85% herd immunity.

A concern if we stay below threshold for a long time is that the virus keeps replicating in the unvaccinated, bouncing into the vaccinated, and giving advantage to any antibody-resistant mutations. We have to stop it replicating as soon as possible. Hopefully that will happen with more vaccines. The mRNA vaccines still look the best to me so far, aside from their difficult cold-chain logistics. They will also be easiest to modify if required. So hopefully that production can step up.

 

[jamil]

Revenue isn't the same thing as profits.

Are you saying that no profit came from the revenue? I don’t see why this is a point to be made. And I really don’t understand the need for this part of the discussion. The government paid for the vaccine. The drug companies are presumably profiting from it, unless their expenses (which they’d mostly write off) were more than the revenue they earned from it. Why is that controversial?

For the one side, it is not evil for a company to profit from government contracts unless there was some sort of crony relationship or fraud.

For the other side, it’s not evil to hold the view that it’s not the government’s place to pay for the vaccines or their development. And yes, the companies may have paid for their research and development, but with the expectation that they’d write most of it off, and eventually turn it into profit from the revenue they’d earn from it.

 

[Ziggidy]

Tonight I heard of another who got sick after #2 shot. Not put an actual number on this but far to many.

You all just go ahead and do you. Me and mine no ******* way OK

I was socializing with a couple of nurses last night and they both got the first one. One got sick with a fever, the other not to bad. What they both stated was they we concerned with the reaction of the second shot; they had heard some (more than just some) we having bad reactions.

I will wait for now.

 

[avboiler11]

Are you saying that no profit came from the revenue?

No.

I don’t see why this is a point to be made.

He claimed $15B in profits for Pfizer from vaccine; that figure was for vaccine revenue, not vaccine income. That’s no so small distinction in the accounting world...

I have zero issues with any company earning a profit from their products, be in an oil company or pharmaceutical or tech company.

My concern is factual accuracy.

Pfizer did not take OpWarpSpeed funding for vaccine development.

Pfizer did get a $1.95B contract for 100M firm doses, and later a follow-on for a second 100M firm doses.

Pfizer’s investor guidance said vaccine will add roughly $15B to top-line 2021 revenue, and about a dime additional earnings per share.

 

[Denny347]

I got my first Pfizer dose yesterday, about 18 hours ago. My arm is slightly tender at the injection site. Zero reactions thus far. If I don't have reactions within the 1st 18 hours, I'll likely not have any. Then again, I had a slightly runny nose when I had COVID so I wasn't expecting much from the vaccine.

 

[Timjoebillybob]

The more time goes by, the more I think Indiana is doing this right by vaccinating the most vulnerable rather than trying to choose "frontline essential". There is legitimate concern that a more contagious variant is developing here, as it did in the UK. If so, it's going to cause another surge before we can get a vaccine in everyone that wants it. By targeting everyone over 60, Indiana is targeting 94% of the deaths and 60% of the hospitalizations. It sounds like after that they might focus on comorbidities rather than age, but are using data to make that decision.

From my understanding IN is doing both, some frontline essential are at the head of the line, med personnel that come in contact with patients, police, fire, ems, etc.

I think the estimated number of previous cases in the US includes about 30% of the population (taking into account asymptomatic, untested).

Herd immunity for a respiratory disease is typically thought to take about 70%. However, the data on increased contagion of new variants looks real. And it makes sense, because such a mutation is going to have an evolutionary advantage for the virus. If the virus is more contagious, it's going to take something closer to 85% herd immunity.

A concern if we stay below threshold for a long time is that the virus keeps replicating in the unvaccinated, bouncing into the vaccinated, and giving advantage to any antibody-resistant mutations. We have to stop it replicating as soon as possible. Hopefully that will happen with more vaccines. The mRNA vaccines still look the best to me so far, aside from their difficult cold-chain logistics. They will also be easiest to modify if required. So hopefully that production can step up.

I understand that, my reply was to Melensdad who said with only 75% being willing to get vaccinated a lot more will have to catch and recover from the rona. My 7.8% number was from confirmed tests. I know the actual number is much higher, but that is only estimated.

How will the rona bounce into the vaccinated? If they are vaccinated they should be pretty much immune right?

 

[GregD]

I just got my first dose of Moderna.

 

[dusty88]

From my understanding IN is doing both, some frontline essential are at the head of the line, med personnel that come in contact with patients, police, fire, ems, etc.

Yes Indiana did vaccinate healthcare workers and first responders. But the "frontline essential" group includes all kinds of careers with general exposure like grocery store workers, teachers, bank tellers etc. Everyone is important, of course, but they can't get all of those people vaccinated at the same time. Indiana CAN probably get most of the 60+ vaccinated before the next surge (if it happens), or at least most of those who choose to sign up.

I understand that, my reply was to Melensdad who said with only 75% being willing to get vaccinated a lot more will have to catch and recover from the rona. My 7.8% number was from confirmed tests. I know the actual number is much higher, but that is only estimated.

How will the rona bounce into the vaccinated? If they are vaccinated they should be pretty much immune right?

Vaccination doesn't prevent the virus from entering your body. When the virus enters someone with immunity, it's going to attempt to use your cells to replicate itself (as viruses do). Some replication may take place before your immune response shuts it down. So the more virus is thrown into the vaccinated, the more likely a random antibody-resistant mutated virus starts replicating in a vaccinated person.

If everybody is vaccinated (or almost everybody) that's less overall replication and less chance of resistant mutations.

 

[Timjoebillybob]

Vaccination doesn't prevent the virus from entering your body. When the virus enters someone with immunity, it's going to attempt to use your cells to replicate itself (as viruses do). Some replication may take place before your immune response shuts it down. So the more virus is thrown into the vaccinated, the more likely a random antibody-resistant mutated virus starts replicating in a vaccinated person.

If everybody is vaccinated (or almost everybody) that's less overall replication and less chance of resistant mutations.

If it's a random antibody-resistant mutated virus, it won't matter if it bounces into a vaccinated person or not. With 30% that have already had it, and 75% immunized I don't see a problem. Heck with 75% and the almost 8% confirmed were close to the 85%. By the time we get to the 75%, I'm sure most of the other 25% will most likely have already contracted it. Considering that 30% of them probably already have.

 

[shadow64]

My son ex-wife and in-laws (all health care workers) have all had both shots with no problems. My 75yr old mom just got her first shot no problems ,so it looks safe for me to get one ! even if there’s a chance to still get covid after the shot it’s still worth it to me.

 

[smokingman]

Johnson & Johnson requests emergency authorization from FDA for Covid vaccine

If J&J's application is approved, it would be the third Covid vaccine authorized for emergency use in the U.S. behind those developed by Pfizer-BioNTech and Moderna.

www.cnbc.com

J&J one-shot non MRNA vaccine emergency use authorization in progress. The final ruling set by the CDC decision is going to be before the end of the month.

This one will not need super cooling either.

J&J one-dose Covid vaccine is 66% effective, a weapon but not a knockout punch

Johnson & Johnson said that its single-dose Covid-19 vaccine reduced rates of moderate and severe disease, but the shot appeared less effective against a new coronavirus variant.

www.statnews.com

66% effective at preventing infection(almost the same as both MRNA vaccines after two doses)
...and 85% effective at reducing symptomatic covid19(vs moderna 95%).

 

[melensdad]

... I understand that, my reply was to Melensdad who said with only 75% being willing to get vaccinated ....

Actually I never said that.
I did quote an article that said 1 in 4 claim they will never take the vaccine.

If you’d bother to read the article it indicated that approx 50% planned to get it. Many were unsure if they’d take it. Some said they would only take it if required.

Do not make invalid conclusions by only looking at a single data point, or worse yet, by reading a misleading headline.

 

[Timjoebillybob]

Actually I never said that.
I did quote an article that said 1 in 4 claim they will never take the vaccine.

If you’d bother to read the article it indicated that approx 50% planned to get it. Many were unsure if they’d take it. Some said they would only take it if required.

Do not make invalid conclusions by only looking at a single data point, or worse yet, by reading a misleading headline.

Here is what you said.

1-in-4 Americans have no intention of getting the vaccine so we will reach herd immunity when a bunch more people get Covid and recover from it, which hopefully times well with vaccinations to reach a high enough level that a combination of infected, recovered & vaccinated people = herd immunity.

I read the article, per the article half intend to get it asap, 6% have already had at least one dose, and 19% "would prefer to let other people get the vaccine first and see how it goes.", 24% would never take it.

So 56% want/have already had it, just under 20% have pretty much the same attitude I have wait and see, and just under 1 in 4 say no way in hell. When you factor in the number that have already had it and recovered, and those that will have and either die or recover before they get that 50% that will be vaccinated, I don't think that 24% and whatever portion of that 19% decide not to will be any kind of factor. Especially considering that there is a confirmed through testing just shy of 8% of the population and an estimated 30% who have already had it.

 

[smokingman]

It is already reported on some media today 2/7/2020,but it is not great news.

The two vaccines tested against B.1.351 south African variant failed to do any better than a placebo in 2000 individuals with an average age of 31.


AstraZeneca says by autumn of 2021 they should have a new vaccine against the South African variant. No comment from Pfizer yet.

The world has 58 available versions of a sars-cov2 vaccine( https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(20)32623-4/fulltext ). Hopefully one of them can fight mutations better than the placebo.

South Africa pauses AstraZeneca vaccine rollout after study shows it offers less protection against variant | CNN

South African health officials said Sunday they're pausing the country's rollout of AstraZeneca's coronavirus vaccine after a study showed it offered reduced protection from the Covid-19 variant first identified there.

www.cnn.com

 

[Denny347]

It is already reported on some media today 2/7/2020,but it is not great news.

The two vaccines tested against B.1.351 south African variant failed to do any better than a placebo in 2000 individuals with an average age of 31.


AstraZeneca says by autumn of 2021 they should have a new vaccine against the South African variant. No comment from Pfizer yet.

The world has 58 available versions of a sars-cov2 vaccine( https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(20)32623-4/fulltext ). Hopefully one of them can fight mutations better than the placebo.

South Africa pauses AstraZeneca vaccine rollout after study shows it offers less protection against variant | CNN

South African health officials said Sunday they're pausing the country's rollout of AstraZeneca's coronavirus vaccine after a study showed it offered reduced protection from the Covid-19 variant first identified there.

www.cnn.com

"But scientists caution that it’s difficult to extrapolate what such lab experiments mean for the real world. The experiments only look at neutralizing antibodies, while the immune response includes other types of antibodies as well as fighters like T cells. With that thinking, it’s possible that the real immune response from vaccines is even more robust against mutations than the lab data show."

 

[GregD]

It has now been a little over 24 hours since I had my first shot.
The only side effect has been a slight tenderness in my arm where I got the shot.

 

[tsm]

About 60 hours now since my first Pfizer shot. Soreness in the injection arm and a mild headache for a little over a day, but nothing otherwise.