Bowling pins might be a good excuse to get a .50AE
Excuse, yes, but I doubt it would do that well. Follow up shots would suck. The fastest guy at MCF&G uses a 6 or 8" S&W 629 with downloaded ammo. It seems to be a great balance of power and speed. The fact he is a great shot helps too.
I usually use a Glock 21 with an Oberland Arms longslide and 6" KKM barrel shooting moderately loaded 230gr. bullets (~850 fps). If I hit them right, they go flying off the table. I can and have shot .45super out of it and I have 500 peices of new .45super brass, but the recoil would seriously screw up my follow up shots.